Timing of blood thinner injection could prevent artery blockage after heart procedure
NCT ID NCT06890312
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether giving the blood thinner heparin before inserting a tube into the wrist artery can prevent a common complication: blockage of that artery. About 550 people undergoing a heart procedure through the wrist will be randomly assigned to receive heparin either before or after the tube is placed. The main goal is to see which timing reduces the risk of artery blockage the next day.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- heparin
- What this could lead to
- If it works, this could lead to a simple change in practice that lowers the risk of radial artery blockage after heart procedures.
- What could go wrong
- This is a relatively small, early-stage study. The timing change may not reduce blockage rates, and there is always a risk of bleeding with heparin.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 550 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients having 18 years old or older, regardless of gender, undergoing percutaneous radial coronary intervention * Subject affiliated to a social protection health insurance * Subject able to understand the objectives and risks of the research and to provide dated and signed consent * Subject who has been informed of the results of the preliminary medical examination Exclusion Criteria: * Contraindication to the use of heparin (history of heparin-induced thrombocytopenia) * Very high bleeding risk defined by recent bleeding (\<6 months) of type 3 of the BARC classification * Subject in an exclusion period (determined by a previous or ongoing study) * Inability to give the subject enlightened information (subject in an emergency situation, difficulties in understanding the subject, etc.) * Subject under safeguard of justice * Subject under guardianship or curatorship * Pregnancy * Breastfeeding * Patient on anticoagulant treatment: anti-vitamin K, direct oral anticoagulants (DOACs).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpitaux Universitaires de Strasbourg
RECRUITINGStrasbourg, Bas-Rhin, 67091, France
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