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Promising drug targets Hard-to-Treat brain metastases in breast and lung cancer

NCT ID NCT05865990

First seen Mar 14, 2026 · Last updated May 24, 2026 · Updated 8 times

Summary

This study tested a drug called HER3-DXd in 63 adults with breast cancer, lung cancer, or other solid tumors that had spread to the brain or the lining around the brain and spinal cord. The goal was to see if the drug could shrink brain tumors or help patients live longer. Participants received the drug every three weeks until their disease got worse or side effects became too severe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Arnau de Vilanova de Valencia

    Valencia, Spain

  • Hospital Beata María Ana

    Madrid, Spain

  • Hospital Quirónsalud Sagrado Corazón

    Seville, Spain

  • Hospital Universitari Dexeus

    Barcelona, Spain

  • Hospital Universitari Vall D'Hebron

    Barcelona, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Spain

  • Medical University of Vienna

    Vienna, Austria

  • Salzburg Cancer research Institute-Center for Clinical Cancer and Immunology Trials

    Salzburg, Austria

Conditions

Explore the condition pages connected to this study.