Engineered immune cells injected directly into brain tumors: a new hope?

This early-phase study tests a new treatment for people with HER2-positive brain tumors that have come back or not responded to standard care. The treatment involves taking a patient's own immune cells (T cells), adding a special antibody (HER2-CAR) to help them recognize and attack tumor cells, and then injecting these cells directly into the tumor or the fluid around the brain. The main goals are to find the safest dose and understand side effects, not yet to prove it works as a cure.