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10,000 liver cancer patients enrolled in massive Real-World study

NCT ID NCT02954094

Knowledge-focused Sponsor: Target PharmaSolutions, Inc. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 10,000 adults with hepatocellular carcinoma (a type of liver cancer) to see how the disease changes over time and how different treatments affect patients in real life. Researchers are collecting information from regular doctor visits and patient surveys, and building a sample bank for future research. The goal is to better understand the disease and improve care, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 10,000 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Dec 2016

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients being managed for HCC

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male or female patients, age ≥18 years 2. Patients with a histological/cytological or radiological diagnosis of HCC (mixed HCC cholangiocarcinoma may be included; patients who are candidates for surgical and non-surgical treatment, as well as those being followed without specific HCC therapy may be included) Exclusion Criteria: 1\. Inability to provide written informed consent

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma Liver Neoplasms pediatric hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hepatocellular cancer

Contacts and locations

Locations

  • A.O.U.P. di Palermo

    Palermo, Italy

  • Banner University Medical Center

    Phoenix, Arizona, 85006, United States

  • Baylor Scott & White All Saints

    Fort Worth, Texas, 76104, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Bon Secours Liver Institute of Virginia

    Richmond, Virginia, 23226, United States

  • CHU de Nice - Hôpital L'Archet 2

    Nice, France

  • California Liver Research Institute

    Pasadena, California, 91105, United States

  • Center for Liver Disease and Transplant at CMC

    Charlotte, North Carolina, 28204, United States

  • Charité - Universitätsmedizin Berlin

    Berlin, Germany

  • Clinical Research Institute@ Methodist Dallas Medical Center

    Dallas, Texas, 75203, United States

  • Clínica Universidad de Navarra

    Pamplona, Spain

  • Columbia University

    New York, New York, 10032, United States

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    Milan, Italy

  • Gastro Florida

    Clearwater, Florida, 33762, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Harborview Medical Center

    Seattle, Washington, 98104, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Hospital Puerta de Hierro Majadahonda

    Madrid, Spain

  • Hospital Universitario Marques de Valdecilla

    Santander, Spain

  • Hospital Universitario Politècnic La Fe

    Valencia, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Spain

  • Humanitas Mirasole IRCCS

    Rozzano, Italy

  • Hôpitaux Universitaires Paris Centre

    Paris, France

  • IRCCS "Casa Sollievo della Sofferenza"

    San Giovanni Rotondo, Italy

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29403, United States

  • Medizinische Hochschule Hannover

    Hanover, Germany

  • Mercy Medical Center, GI Research

    Baltimore, Maryland, 21202, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Northwell Health - Center for Liver Diseases

    Manhasset, New York, 11030, United States

  • Northwestern University Division of Gastroenterology and Hepatology

    Chicago, Illinois, 60611, United States

  • Penn State Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Piedmont Atlanta Hospital

    Atlanta, Georgia, 30309, United States

  • Piedmont Cancer Institute

    Atlanta, Georgia, 30318, United States

  • Providence Health & Services Cancer Clinical Trials

    Portland, Oregon, 97213, United States

  • Research Specialists of Texas

    Houston, Texas, 77030, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Rutgers-Robert Wood Johnson Medical School

    New Brunswick, New Jersey, 08901, United States

  • Saint Louis University

    St Louis, Missouri, 63110, United States

  • Schiff Center for Liver Diseases/University of Miami

    Miami, Florida, 33136, United States

  • Southern Therapy and Advanced Research (STAR) LLC

    Jackson, Mississippi, 39216, United States

  • Stanford University

    Palo Alto, California, 94304, United States

  • Tampa General Medical Group

    Tampa, Florida, 33606, United States

  • Tulane University

    New Orleans, Louisiana, 70112, United States

  • University of Arkansas

    Little Rock, Arkansas, 72205, United States

  • University of California

    San Francisco, California, 94158, United States

  • University of California-Davis

    Sacramento, California, 95817, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Florida Health Gastroenterology

    Jacksonville, Florida, 32207, United States

  • University of Florida Hepatology Research at CTRB

    Gainesville, Florida, 32610-0272, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68106, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Southern California/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-8887, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

  • University of Wisconsin

    Madison, Wisconsin, 53705-2281, United States

  • Universitätsklinikum Aachen

    Aachen, Germany

  • Universitätsklinikum Düsseldorf

    Düsseldorf, Germany

  • Universitätsklinikum Frankfurt

    Frankfurt, Germany

  • Universitätsklinikum Leipzig

    Leipzig, Germany

  • Universitätsklinikum Magdeburg

    Magdeburg, Germany

  • Universitätsmedizin Mainz

    Mainz, Germany

  • Vanderbilt University Medical Center - GI Research Office

    Nashville, Tennessee, 37212, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

  • Weill Cornell Medical College

    New York, New York, 10021, United States

  • Wenatchee Valley Hospital & Clinics

    Wenatchee, Washington, 98801, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.