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Air purifiers tested to soothe baby lungs after bronchiolitis

NCT ID NCT05615870

Disease control Sponsor: IDeA States Pediatric Clinical Trials Network Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using HEPA air filters at home can reduce respiratory symptoms in infants under 12 months who were hospitalized for bronchiolitis. 230 babies were randomly assigned to have either real HEPA filters or placebo filters in their home for 24 weeks. Caregivers tracked days without coughing, wheezing, or trouble breathing. The goal is to see if cleaner indoor air helps babies recover faster and avoid more doctor visits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
HEPA filtration unit
What this could lead to
If effective, using HEPA filters at home could reduce coughing, wheezing, and breathing trouble in infants after bronchiolitis.
What could go wrong
This is a completed trial, but results are not yet published. The benefit may be small or not apply to all infants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

230 people

The number who actually took part.

Started

Nov 2022

Finished

Jul 2024

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 week to 12 months

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \<12 months at hospital admission * First-time hospitalization for bronchiolitis * One primary residence (\>5 days per week) * Parent, legal guardian or other legally authorized representative consents to allow their child to participate and agrees to participate in all study activities * Electricity in the home (required to power the study equipment) * Wireless internet access or cellular service access in the home\* * English or Spanish-speaking parent or guardian Exclusion Criteria: * Chronic airway or respiratory conditions requiring home oxygen, mechanical ventilation, or tracheostomy dependence; known immunodeficiency, hemodynamically significant cardiac conditions including those requiring medication or oxygen; cystic fibrosis; neuromuscular disease; eligible for palivizumab (per AAP guidelines87) * Use of stand-alone home HEPA filtration other than study-related HEPA units in the home * Household member who smokes (any type), vapes, or uses e-cigarettes * Intention to move in the next 6 months * Enrolled or plans to enroll in an interventional clinical trial for treatment of acute bronchiolitis or sequelae of bronchiolitis, unless permission given by the PI * Another child in the household is enrolled in this study (one child per household can enroll)

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Conditions

The condition(s) this trial relates to.

bronchiolitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bronchiolitis

Contacts and locations

Locations

  • Alaska Native Tribal Health Consortium

    Anchorage, Alaska, 99508, United States

  • Arkansas Children's Hospital - Little Rock (ACHRI)

    Little Rock, Arkansas, 72202, United States

  • Avera Research Institute

    Sioux Falls, South Dakota, 57108, United States

  • Children's Hospital OU Medical Center

    Oklahoma City, Oklahoma, 73104, United States

  • Dartmouth Hospital

    Lebanon, New Hampshire, 03756, United States

  • Kansas University Medical Center

    Kansas City, Kansas, 66160, United States

  • Kapi'olani Medical Center for Women and Children

    Honolulu, Hawaii, 96826, United States

  • Prisma Health-Midlands

    Columbia, South Carolina, 29203, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Tulane University, Department of Pediatrics

    New Orleans, Louisiana, 70112, United States

  • University of Louisville

    Louisville, Kentucky, 40292, United States

  • University of Miss. Medical Center

    Jackson, Mississippi, 39216, United States

  • University of Montana

    Missoula, Montana, 59812, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of New Mexico Health Sciences Center

    Albuquerque, New Mexico, 87131, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.