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Does your own blood carry oxygen better than donor blood? a new trial investigates

NCT ID NCT07677150

Knowledge-focused Sponsor: Medical University Innsbruck Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study looks at how well red blood cells carry oxygen after being processed from a patient's own lost blood during surgery, compared with standard donor blood transfusions. Researchers want to see if the patient's own blood, collected and cleaned by a machine called a cell saver, delivers oxygen more efficiently than stored donor blood. The trial involves adults having major surgery who are likely to need a blood transfusion. Understanding this could help improve how blood is handled before transfusion.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
autologous blood from intraoperative cell salvage
What this could lead to
If cell-salvaged blood proves better at delivering oxygen, it could improve patient recovery after major surgery and reduce reliance on donor blood.
What could go wrong
This is a small pilot study, so results may not be conclusive. The procedure requires special equipment and may not be suitable for all surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 418 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Understands and agrees to comply with the study procedures and provides written informed consent as documented by signature. 2. Female and male subjects ≥ 18 years of age at time of consent. 3. Patient undergoes elective surgery according to Surgery List in Protocol Appendix and blood transfusion is likely to happen at the discretion of the investigator. Inclusion criterion 4 only refers to WOCBP 4. Negative urine pregnancy test, not breastfeeding Exclusion Criteria: 1. Known hemoglobinopathy 2. Indication for irradiation of blood products 3. preoperative Anemia (Hb \<11 mg/dl for women and Hb \<12 mg/dl for men) 4. Contraindication for intraoperative cell salvage (septic surgery, tumor surgery) 5. Contraindication for transesophageal Doppler ultrasound (craniofacial dysplasia or fracture, history of esophageal perforation or rupture, esophageal stricture, esophageal varices)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bleeding as surgical complication (treatment)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medical University Innsbruck

    Innsbruck, Tyrol, 6020, Austria

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