Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Should hip fracture patients on blood thinners get surgery right away?

NCT ID NCT07309848

Knowledge-focused Sponsor: St. Antonius Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at 374 hip fracture patients who take blood thinners (DOACs). Doctors often delay surgery due to bleeding concerns, but waiting may cause other problems. The study compares early surgery (within 24 hours) to delayed surgery to see if early surgery increases the need for blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors decide the safest timing for hip fracture surgery in patients on blood thinners, potentially reducing complications and hospital stays.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by other factors. It only looks at transfusion risk, not other outcomes like mortality or recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 374 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study participants will be selected from patients admitted with an isolated hip fracture to one of seven Dutch level 2 trauma centers. All patients are routinely treated according to local hospital protocols, which differ in surgical timing policies for patients on direct oral anticoagulants. This natural variation provides the basis for the study cohorts (\<24h vs \>24h to surgery).

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Isolated hip fracture classified as AO/OTA 31A or 31B requiring surgical intervention. * Current DOAC use with the last dose taken ≤24 hours before emergency department (ED) presentation Exclusion Criteria: * Pathologic or periprosthetic hip fractures. * Fracture sustained \>24 hours before ED presentation. * Inter-hospital transfer. * Hematologic disorders (e.g., thalassemia, sickle cell disease, aplastic anemia, myelodysplastic syndromes, leukemia). * Use of a non-EMA-approved DOAC (e.g., betrixaban).

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Bleeding are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Hemorrhage hemorrhagic disease hip fracture Transfusion Reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bleeding Bleeding as surgical complication (treatment) Bleeding complications Blood transfusion Blood transfusion complication Blood transfusions Direct oral anticoagulants (doacs) Geriatric Hip fracture surgeries

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Deventer Hospital

    RECRUITING

    Deventer, Netherlands

  • Diakonessenhuis Hospital

    RECRUITING

    Utrecht, Netherlands

  • Martini Hospital

    RECRUITING

    Groningen, Netherlands

  • Onze Lieve Vrouw Gasthuis Hospital

    RECRUITING

    Amsterdam, Netherlands

  • Rijnstate Hospital

    RECRUITING

    Arnhem, Netherlands

  • St. Antonius Hospital

    RECRUITING

    Utrecht, Netherlands

  • Ziekenhuisgroep Twente Hospital

    RECRUITING

    Almelo, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.