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Wrist-to-Bottom procedure could replace hemorrhoid surgery

NCT ID NCT06175325

Symptom relief Sponsor: University Hospitals of North Midlands NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tests a procedure called trans-radial superior rectal artery embolisation for treating hemorrhoids. Instead of surgery, doctors access an artery in the wrist to block blood flow to the hemorrhoid, which may reduce bleeding and pain. The study will enroll 20 adults with grade II-IV hemorrhoids and follow them for 24 months to check safety and symptom improvement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Trans-radial superior rectal artery embolisation (a procedure using tiny particles to block blood flow to hemorrhoids)
What this could lead to
If it works, this could offer a less painful, same-day alternative to surgery for people with bleeding hemorrhoids.
What could go wrong
This is a very small pilot study with only 20 people, so results may not apply to everyone. The procedure is still experimental and long-term safety is not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients eligible for the study must comply with all of the following prior to enrolment: * Patients with grade II-IV haemorrhoid disease with re-current or active bleeding * Patients with (i) who do not wish to undergo surgery for their symptoms * Patients with (i) despite recent surgery * Patients willing and able to give fully informed consent * Patients aged ≥18 years Exclusion Criteria: * Patients who are not otherwise fit for surgery * Patients with significant ano-rectal comorbidities (cancer, fistula, abscesses) * Patient who are unable to sign the informed consent form. * Patients who are pregnant (completed as part of standard IRMER protocol) * Patients with history of significant colorectal disease or previous colectomy. * Patients with history of an allergic reaction to x-ray contrast * Patients who are currently involved in research

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Conditions

The condition(s) this trial relates to.

hemorrhoid

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemorrhoids

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospitals of North Midlands NHS Trust

    RECRUITING

    Stoke-on-Trent, United Kingdom

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