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Could a dialysis filter help heart attack survivors?

NCT ID NCT00780299

Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a special type of dialysis (high-permeability hemodialysis) could help people in shock after being revived from cardiac arrest. The idea was to filter out inflammatory substances from the blood to improve blood pressure and reduce the need for strong medications. The trial included 38 comatose patients in intensive care and measured how long they needed shock treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hemodialysis with high permeability (HDHP)
What this could lead to
If it works, this could point toward a way to reduce shock duration and organ failure after cardiac arrest.
What could go wrong
This is a small, completed Phase 3 trial with only 38 participants, so results may not apply broadly. The intervention is complex and may not improve outcomes over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

38 people

The number who actually took part.

Started

Nov 2008

Finished

Jan 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria * Comatous patients admitted to the ICU for a sudden cardiac death apparently related to heart disease and requiring catecholamine infusion to treat a shock * Cardiac arrest in front of witnesses * Written informed consent obtained from the family or by emergency procedure Exclusion criteria * Age under 18 years * Response to verbal commands (Glasgow score \>7) * Terminal illness present before the cardiac arrest * Acquired or innate immune deficit * Anticoagulation not recommended or high hemorrhagic risk * pregnancy * weight \> 100 kg * without social security * another clinical trial ongoing * cardiac arrest from non cardiac etiology

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Conditions

The condition(s) this trial relates to.

cardiac arrest cardiogenic shock Death, Sudden, Cardiac post-cardiac arrest syndrome Shock sudden arrhythmia death syndrome sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac arrest Shock Sudden cardiac death

Contacts and locations

Locations

  • Medical intensive care unit of Cochin-St Vincent de Paul university Hospital

    Paris, 75679, France

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