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Can a simple drug save more donor kidneys from failing?

NCT ID NCT03646344

First seen Nov 17, 2025 · Last updated May 24, 2026 · Updated 27 times

Summary

This study tested whether the drug heme arginate could help transplanted kidneys start working right away, instead of being delayed. It included 47 adults receiving a deceased-donor kidney transplant. Participants got either heme arginate or a placebo (salt water) at the time of transplant and again 24 hours later. The trial was stopped early, so results are limited, but early findings suggested the drug might reduce kidney injury.

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Contacts and locations

Locations

  • Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh

    Edinburgh, EH16 4UX, United Kingdom

  • NHS Lothian - Royal Infirmary of Edinburgh

    Edinburgh, Lothian, EH16 4SA, United Kingdom

Conditions

Explore the condition pages connected to this study.