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New braces wire may straighten teeth faster and with less pain

NCT ID NCT07176871

Symptom relief Sponsor: Can Tho University of Medicine and Pharmacy Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether heat-activated nickel-titanium (HANT) archwires straighten teeth better than conventional nickel-titanium wires in people with braces. Fifty-two patients aged 16 to 25 with crowded upper front teeth were randomly assigned to one wire type. Researchers measured how quickly teeth aligned over 6 months, checked root and bone health with 3D scans, and recorded pain levels. The goal was to see if HANT wires offer a more efficient and comfortable orthodontic experience.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
heat-activated nickel-titanium (HANT) archwires
What this could lead to
If HANT wires prove more effective, they could become a standard option for faster, more comfortable teeth straightening in braces.
What could go wrong
This is a small, completed trial with only 52 patients, so results may not apply to everyone. The difference between wire types might be small or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Jul 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients with Class I malocclusion on both sides * aged between 16 and 25 years with permanent dentition * bilateral extraction of the maxillary first premolar * maxillary Little's irregularity index between 7-9 mm * patients with no periodontal disease. Exclusion Criteria: * Patients who had previous orthodontic treatment, * spacing in the maxillary anterior region * suffer from bleeding disorders, diabetes, bone diseases, periodontal disease, and cancer, as well as those using drugs (such as aspirin, heparin, warfarin, nonsteroidal anti-inflammatory drugs, and glucocorticoids) * Patients with trauma and facial deformities, smokers, or pregnant were excluded from the study.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic

Contacts and locations

Locations

  • Can Tho University of Medicine and Pharmacy

    Can Tho, 90000, Vietnam

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