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Blood test may replace painful heart biopsies for transplant patients

NCT ID NCT06414603

First seen Feb 28, 2026 · Last updated May 19, 2026 · Updated 7 times

Summary

This study compares a simple blood test (Prospera) to the standard heart biopsy for checking organ rejection in heart transplant patients. About 250 adults waiting for or who have received a heart transplant will take part. The goal is to see if the blood test is as good or better at detecting rejection, which could reduce the need for invasive procedures.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AdventHealth Orlando

    Orlando, Florida, 32804, United States

  • Baylor Scott White - Temple

    Temple, Texas, 76508, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Inova Schar Heart and Vascular Institute

    Falls Church, Virginia, 22042, United States

  • Kansas University Medical Center

    Kansas City, Kansas, 66160, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • University of California, San Diego

    San Diego, California, 92103, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Texas, Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.