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Heart drug combo may boost recovery after valve surgery

NCT ID NCT07539259

First seen Apr 29, 2026 · Last updated May 21, 2026 · Updated 3 times

Summary

This study tests whether two heart failure medications, dapagliflozin and spironolactone, can help the heart recover more fully after aortic valve replacement. About 445 adults with severe aortic stenosis will take one or both drugs daily for 12 months after their valve surgery. The goal is to see if these medicines reduce heart muscle thickness and scarring, improving long-term heart function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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