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Heart study reveals hidden link between blood vessels and muscle blockage

NCT ID NCT04129905

Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how blood vessel function relates to heart blockage in people with a genetic heart condition called hypertrophic cardiomyopathy. Researchers measured blood flow and vessel flexibility in 40 adults. The goal was to understand the connection, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Oct 2019

Finished

Dec 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients and volunteers: * Adults (age ≥18 years), male or female, * For female in age, efficient contraception will be required and a negative pregnancy test will be required, * Signed informed consent form will required for each included subject after having read the information note, * Affiliated to the national social security system, * Patients: .Patients diagnosed to have HCM secondary to sarcomeric mutation or to Fabry disease, symptomatic (dyspnea on exertion and/or chest pains during exercise), * Healthy volunteers: * Subjects without known cardiac disease, * No smokers. Exclusion Criteria: * Patients and volunteers: * No cardiac pathology reducing life expectancy to less than 12 months (cancer), * Unbalanced arterial hypertension (systolic \>160 mmHg and/or diastolic \>120 mmHg), * Pregnancy or breastfeeding, * Major obesity \> 140 kg, * Impossibility or refusal to give or sign the consent form, * Subject in period of exclusion relative to an other protocol, * Subject deprived of liberty by judicial or administrative decision, * Major protected by the Law * Patients: * Atrial fibrillation at the time of inclusion * Valvulopathy with severity greater than moderate.

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Conditions

The condition(s) this trial relates to.

Fabry disease hypertrophic cardiomyopathy Ventricular Outflow Obstruction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endothelial dysfunction Hypertrophic cardiomyopathy

Contacts and locations

Locations

  • University Hospital, Bordeaux

    Pessac, 33604, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.