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New ultrasound technique spots hidden heart trouble in kids on dialysis

NCT ID NCT07678710

Knowledge-focused Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests whether advanced ultrasound techniques (2D and 3D speckle-tracking echocardiography) can detect early signs of heart muscle dysfunction in children aged 4 to 18 with end-stage kidney disease who have been on dialysis for at least a year. Researchers aim to see if these methods are more sensitive than standard heart ultrasound for identifying heart problems before they become severe. The study does not involve any drug or treatment—it is purely observational, using non-invasive imaging to gather knowledge.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to earlier detection of heart problems in children with kidney disease, potentially improving their long-term care.
What could go wrong
This is a small observational study with only 20 children, so results may not apply to all patients. The technique is also highly dependent on image quality.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Jan 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This prospective observational study was conducted at the pediatric cardiology and nephrology units of Al-Hussain and Bab El-Shaaria University Hospitals, Al-Azhar University, Cairo, Egypt from January 2025 to August 2025.

Ages

4 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 4 and 18 years. * Children with chronic kidney disease (CKD) receiving regular hemodialysis for ≥1 year. Exclusion Criteria: * Presence of structural or congenital heart disease. * Patients with poor echocardiographic window or arrhythmias interfering with image acquisition.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Children End stage kidney disease Left ventricular myocardial dysfunction Three-dimensional speckle-tracking echocardiography Two-dimensional speckle-tracking echocardiography

Contacts and locations

Locations

  • Al-Azhar University

    Cairo, 11651, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.