Could two pacing leads be better than one for failing hearts?
NCT ID NCT07526896
First seen Apr 28, 2026 · Last updated Jun 19, 2026 · Updated 6 times
Summary
This study compares two pacing methods in 80 people with heart failure and a specific heart block. One method uses a lead placed in the left bundle branch area; the other adds a second lead in the left ventricle. Each participant will try both methods for six months to see which improves heart function and quality of life more.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cardiac resynchronization therapy defibrillator (CRT-D) programmed for left bundle branch area pacing (LBBAP) or combined with left ventricular lead pacing (LOT-CRT)
What this could lead to
If successful, this could show that combining two pacing methods improves heart pumping and quality of life more than one method alone.
What could go wrong
This is a small, early feasibility study with only 80 participants. It may not prove long-term benefit, and results might not apply to all heart failure patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.