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New study aims to find best heart attack care for seniors with multiple blockages

NCT ID NCT03772743

Disease control Sponsor: Consorzio Futuro in Ricerca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two ways to treat heart attacks in people aged 75 and older who have several blocked heart arteries. One approach only fixes the artery that caused the heart attack, while the other uses a special test to decide which other blockages to open. The goal is to see which method helps patients live longer and have fewer heart problems. About 1,445 participants are being followed for at least one year.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,445 people

The number who actually took part.

Started

Jul 2019

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

75 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients ≥75 years AND 2. MI (ST-segment elevation or not ST.segment elevation MI) with indication to invasive management AND 3. Multi-vessel disease defined as at least 1 non-culprit coronary artery lesion at least 2.5 mm in diameter deemed at visual estimation with a diameter stenosis % ranging from 50 to 99% amenable to successful treatment with PCI AND 4. Successful treatment of culprit lesion Exclusion Criteria: 1. Planned surgical revascularization 2. Non-cardiovascular co-morbidity reducing life expectancy to \< 1 year 3. Any factor precluding 1-year follow-up 4. Prior Coronary Artery Bypass Graft (CABG) Surgery 5. Impossibility to identify a clear culprit lesion 6. Non culprit lesion located in the left main

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Conditions

The condition(s) this trial relates to.

myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myocardial infarction

Contacts and locations

Locations

  • AO Cannizzaro

    Catania, Italy

  • AOU Ferrara

    Ferrara, Ferrara, 44124, Italy

  • AOU Gaetano Martino

    Messina, Italy

  • AOU Giaccone

    Palermo, Italy

  • AOU Integrata di Verona

    Verona, Italy

  • AOU Sant'Andrea

    Roma, Italy

  • AOU Sant'Anna e San Sebastiano

    Caserta, Italy

  • ASP Agrigento

    Agrigento, Italy

  • Arcispedale Santa Maria Nuova

    Reggio Emilia, Reggio Emilia, Italy

  • Casa di Cura San Michele Maddaloni

    Caserta, Italy

  • Centrum Kardiologii Inwazyjnej Elektroterapii i Angiologii

    Oświęcim, Poland

  • Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii

    Krosno, Poland

  • Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii

    Nowy Sącz, Poland

  • Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii

    Pińczów, Poland

  • Complejo Hospitalario Universitario de Santiago

    Santiago de Compostela, Spain

  • Complejo Hospitalario de La Coruna

    A Coruña, Spain

  • Hospital Alvaro Conqueiro de Vigo

    Vigo, Spain

  • Hospital Clinico San Carlos

    Madrid, Spain

  • Hospital Clinico Universitario

    Valladolid, Spain

  • Hospital General Universitario Gregorio Maranon

    Madrid, Spain

  • Hospital General Universitario de Ciudad Real

    Ciudad Real, Spain

  • Hospital Universitario La FE

    Valencia, Spain

  • Hospital Universitario La Paz

    Madrid, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, Spain

  • Maria Cecilia Hospital

    Cotignola, Ravenna, Italy

  • Ospedale Civile di Baggiovara

    Modena, Italy

  • Ospedale Infermi

    Rimini, Rimini, Italy

  • Ospedale Maggiore

    Bologna, Bologna, Italy

  • Ospedale SS Annunziata

    Savigliano, Italy

  • Ospedale Sant.Andrea

    La Spezia, Italy

  • Ospedale Santa Croce

    Moncalieri, Italy

  • Ospedale Santa Maria delle Croci

    Ravenna, Ravenna, Italy

  • Ospedale Umberto I

    Syracuse, Italy

  • Ospedale dell'Angelo

    Mestre, Italy

  • Ospedale della Misericordia

    Grosseto, Italy

  • Ospedale di Rivoli

    Torino, Italy

  • Podkarpackie Centrum Interwencji Sercowo-Naczyniowych

    Sanok, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.