Heart registry hopes to personalise treatment for 1-in-500 condition
NCT ID NCT07381894
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is a national registry in the UK that collects health information from 2500 people with hypertrophic cardiomyopathy (HCM), a common inherited heart condition. Researchers will gather data from medical records, heart scans, blood tests, and genetics to better understand the disease and improve risk prediction. The goal is to help doctors personalise treatments for each patient in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this registry could help doctors better predict which treatments work best for each person with hypertrophic cardiomyopathy, leading to more personalised care.
- What could go wrong
- This is an observational registry, not a treatment trial. It collects existing data and does not test any new therapy, so it cannot directly improve health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jan 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants with a confirmed diagnosis of hypertrophic cardiomyopathy will be recruited.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed diagnosis of Hypertrophic Cardiomyopathy (HCM) clinically and not solely explained by abnormal loading conditions (e.g., significant hypertension, valvular disease Exclusion Criteria: * Participants who do not fulfil the imaging and clinical diagnostic criteria of HCM
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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University of Manchester
RECRUITINGManchester, M23 9LT, United Kingdom
Contact Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- 3,000 hearts, one goal: mapping how hypertrophic cardiomyopathy unfolds in china
- Heart scan AI could predict sudden cardiac death risk in common heart condition
- Experimental pill aims to ease thick heart muscle symptoms
- Massive HCM database aims to unlock better heart care
- Heart drug swap tested for safer symptom control
- Real-World HCM drug use under the microscope