New supplement shows promise for stronger muscles in seniors
NCT ID NCT07402278
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a daily supplement called HB05P can safely improve muscle strength in adults aged 60 to 79 who have age-related muscle weakness. Eighty participants took either HB05P or a placebo for 12 weeks, and everyone did regular walking and resistance exercises. The main goal was to measure changes in leg muscle strength using a special machine.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Mar 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 79 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 60 years or older and younger than 80 years (male or female) who meet the inclusion criteria and do not meet any exclusion criteria * Body Mass Index (BMI) between 18.5 and 30.0 kg/m² * Skeletal muscle mass less than 110% of standard value measured by Bioelectrical Impedance Analysis (BIA) * Reduced handgrip strength in the dominant hand based on age- and sex-specific criteria: (Ages 60-69) Males ≤38.5 kg, Females ≤24.1 kg; (Ages 70-79) Males ≤33.2 kg, Females ≤20.9 kg * Capable of normal physical activity and voluntarily providing written informed consent to participate in this study Exclusion Criteria: * History of bone fracture within the past 1 year * Serum creatinine greater than 2 times the upper limit of normal at the study site * AST (GOT) or ALT (GPT) greater than 2 times the upper limit of normal at the study site * Current diabetes mellitus or fasting blood glucose ≥126 mg/dL * Uncontrolled hyperthyroidism or hypothyroidism * Uncontrolled hypertension (blood pressure ≥160/100 mmHg) * Currently taking medication for psychiatric disorders (except for intermittent use for sleep disorders) * Participation in another drug clinical trial within 1 month prior to screening * Regular consumption (≥4 times/week) of probiotics or fermented dairy products (yogurt, cheese, etc.) within 2 weeks prior to screening * Use of medications or health functional foods related to muscle function within 1 month prior to screening (refer to prohibited concomitant medications) * History of gastrointestinal resection surgery (except appendectomy) * Pregnant or lactating women, or women planning to become pregnant during the study period * Known allergy to any component of the study product * History of alcohol abuse * Asthma or obstructive/restrictive pulmonary disease that may affect lung volume * Uncooperative attitude or any condition that, in the investigator's judgment, would make the participant unsuitable for the study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chung-Ang University Hospital
Seoul, South Korea
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