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Squeeze your way to better health? handgrip exercise trial for seniors with high blood pressure

NCT ID NCT07648498

Symptom relief Sponsor: McMaster University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a short, supervised handgrip exercise program is practical and enjoyable for older adults (65+) with high blood pressure. Thirty participants will do handgrip exercises twice a week for 4 weeks. Researchers will check if the program is easy to stick with and if it leads to any improvements in blood pressure and cognitive function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
isometric handgrip exercise using the Zona Plus device
What this could lead to
If this works, it could offer a simple, low-cost exercise option to help older adults manage blood pressure and potentially boost cognitive function.
What could go wrong
This is a very small, early feasibility study with only 30 participants. It is not designed to prove the exercise works, only that it is acceptable and practical. Results may not apply to all older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 65 years of age or older * Currently attending the Physical Activity Centre of Excellence at McMaster University * English speaking * Diagnosed with hypertension or elevated blood pressure Exclusion Criteria: * Current or prior participation in chronic isometric exercise * Unstable angina. * Uncontrolled hypertension * Uncontrolled heart failure and/or arrhythmias * Recent myocardial infarction or electrocardiography changes * Complete heart block * Carpal tunnel syndrome * Arthritis that may be aggravated by handgrip exercise * Changes to the type and/or dose of blood pressure medications within 3 months of starting the study.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Elevated blood pressure Hypertension

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • NeuroFit Lab, Ivor Wynne Centre, McMaster University

    Hamilton, Ontario, Canada

  • Physical Activity Centre of Excellence, Ivor Wynne Centre, McMaster University

    Hamilton, Ontario, Canada

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