Could half a dose be enough? new study tests lighter blood thinner after stents
NCT ID NCT07622056
First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 2 times
Summary
This study tested whether a half-dose blood thinner (ticagrelor) taken alone after heart stent placement works as well as the standard two-drug therapy in East-Asian patients with chronic coronary syndrome. Sixty participants were randomly assigned to one of three treatment groups. The main goal was to measure how well the drugs prevented blood clots, while also watching for bleeding risks. Results may help tailor safer, simpler treatment for this population.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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54 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adults with CCS, defined per the 2019 ESC criteria, scheduled for elective PCI on the day after admission * able to provide consent Exclusion Criteria: * ACS at presentation * Prior intolerance to any study drug * Active bleeding or BARC ≥ 3 bleeding within three months, * NYHA IV heart failure * Platelet count below 100 × 10⁹/L * eGFR below 30 mL/min/1.73 m² * Severe hepatic dysfunction * Planned non-cardiac surgery within twelve months * Patient who inabley to provide consent. * Patients in whom PCI was not performed at the index procedure (per protocol)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kaohsiung Veterans General Hospital
Kaohsiung City, 813414, Taiwan
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Other studies related to the condition(s) this trial covers.
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