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Gel after tooth pull may stop painful dry socket

NCT ID NCT07139340

Disease control Sponsor: Delta University for Science and Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests whether placing a hyaluronic acid gel into the empty socket after lower wisdom tooth removal can prevent dry socket—a painful condition where the blood clot fails to form or is lost. The study includes 64 healthy adults who need a lower wisdom tooth extracted. Researchers will compare dry socket rates and pain levels between those who receive the gel and those who do not.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hyaluronic acid gel
What this could lead to
If it works, this simple gel could become a routine step after wisdom tooth removal to prevent dry socket and reduce pain.
What could go wrong
This is a small, early study with only 64 participants. The gel may not lower dry socket rates, and results may not apply to smokers or people with poor oral hygiene.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

Aug 2021

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 33 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy patients (ASA=1) * Patients need extraction of mandibular third molar * Patients can attend recalls Exclusion Criteria: * Smoking patients * Patients taking oral contraceptive pills * Bad oral hygiene

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Conditions

The condition(s) this trial relates to.

alveolar periostitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar osteitis

Contacts and locations

Locations

  • Delta university for science and technology

    Gamasa, Dakahlia Governorate, 7731168, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.