Gel after tooth pull may stop painful dry socket
NCT ID NCT07139340
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This trial tests whether placing a hyaluronic acid gel into the empty socket after lower wisdom tooth removal can prevent dry socket—a painful condition where the blood clot fails to form or is lost. The study includes 64 healthy adults who need a lower wisdom tooth extracted. Researchers will compare dry socket rates and pain levels between those who receive the gel and those who do not.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hyaluronic acid gel
- What this could lead to
- If it works, this simple gel could become a routine step after wisdom tooth removal to prevent dry socket and reduce pain.
- What could go wrong
- This is a small, early study with only 64 participants. The gel may not lower dry socket rates, and results may not apply to smokers or people with poor oral hygiene.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
64 people
The number who actually took part.
- Started
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Aug 2021
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 33 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy patients (ASA=1) * Patients need extraction of mandibular third molar * Patients can attend recalls Exclusion Criteria: * Smoking patients * Patients taking oral contraceptive pills * Bad oral hygiene
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Delta university for science and technology
Gamasa, Dakahlia Governorate, 7731168, Egypt
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Other studies related to the condition(s) this trial covers.