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Can a Patient's own blood beat a standard dressing for dry socket?

NCT ID NCT07790653

Disease control Sponsor: CMH Lahore Medical College and Institute of Dentistry Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Sep 02, 2026 · Updated 4 times

Summary

This trial tests two treatments for dry socket, a painful complication after tooth extraction. One is Alvogyl, a standard medicated dressing. The other is platelet-rich fibrin (PRF), made from the patient's own blood, which may help tissue heal. About 102 adults with dry socket will receive one of the two treatments. Researchers will compare pain levels and socket healing on days 1 and 3 to see if PRF offers better results.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Alvogyl dressing or platelet-rich fibrin (PRF) made from the patient's own blood
What this could lead to
If PRF works better, it could offer a more effective way to ease pain and speed healing for people with dry socket.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. PRF requires extra blood draws and preparation, and healing outcomes can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

102 people

The number who actually took part.

Started

Feb 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged 18 years or older. 2. Participants of either sex. 3. Patients presenting with alveolar osteitis following third molar extraction, diagnosed according to the study's operational definition. 4. Patients willing to participate in the study and provide informed consent. 5. Patients willing and able to attend the scheduled postoperative follow-up assessments. Exclusion Criteria: 1. Patients with a smoking habit. 2. Patients with a history of bleeding disorders. 3. Patients unwilling or unable to attend the required follow-up sessions. 4. Patients with a history of hypertension, diabetes mellitus, liver disease, or renal disease. 5. Pregnant or breastfeeding individuals. 6. Patients using medications that may affect healing or study outcomes, including bisphosphonates, systemic steroids, or antidepressants.

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Conditions

The condition(s) this trial relates to.

alveolar periostitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar osteitis

Contacts and locations

Locations

  • CMH Lahore

    Lahore, Pakistan

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