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New drug cocktail aims to stop deadly transplant complication

NCT ID NCT06315309

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 32 times

Summary

This study tests whether a new way of giving three drugs (ATG, tacrolimus, and methotrexate) can prevent a serious side effect called graft-versus-host disease (GVHD) after a stem cell transplant for blood cancers. The trial will enroll 29 adults aged 18-60 who have a matched donor. The goal is to see if this approach helps patients stay alive and free of severe GVHD or cancer relapse one year after transplant.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

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Conditions

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