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Gut health linked to Kids' respiratory infections in new study

NCT ID NCT07378852

Knowledge-focused Sponsor: Min-Tze LIONG Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will examine gut bacteria, immune markers, and nutrient levels in 120 children with different respiratory health conditions, including pneumonia and recurrent infections, compared to healthy kids. By analyzing stool samples and health data, researchers hope to understand how gut health influences respiratory illness. The study is observational, meaning it will not test any treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how gut health affects respiratory infections in children, pointing toward new ways to prevent or manage these illnesses.
What could go wrong
This is an observational study, not a treatment trial. It will not test any therapy, and findings may not lead to direct medical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children from all cohorts will be recruited from the pediatric clinics of the 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army

Ages

3 to 14 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Aged 3-14 years; 2. Good compliance and complete clinical data; 3. Guardians are informed and sign written consent; 4. MPP group: meets diagnostic criteria of Guidelines for Diagnosis and Treatment of Mycoplasma Pneumoniae Pneumonia in Children (2023 Edition); 5. NMP group: acute respiratory tract infection with negative MP-DNA/RNA; 6. RRTIs group: meets diagnostic criteria of Clinical Diagnosis and Treatment Pathway for Recurrent Respiratory Tract Infections in Children (2022 Edition); 7. Healthy controls: no respiratory infection history within the past month. Exclusion Criteria 1. Other infectious diseases (e.g., measles, pertussis, tuberculosis); 2. Congenital heart disease, immunodeficiency, or major organ dysfunction; 3. Use of antibiotics, probiotics, immunomodulators, hormones, or microecological preparations within the past 15-30 days; 4. Unqualified biological samples or incomplete laboratory data.

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Conditions

The condition(s) this trial relates to.

Mycoplasma pneumoniae pneumonia respiratory system disorder respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Respiratory

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army

    Lanzhou, Gansu, 730000, China

  • Universiti Sains Malaysia

    Pulau Pinang, Pulau Pinang, 11800, Malaysia

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