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Fiber from fungus could boost gut health, early study hints

NCT ID NCT03773900

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether taking a daily fiber supplement called chitin-glucan for three weeks could change gut bacteria and improve health markers in 19 adults with abdominal obesity and cardiometabolic risk. Participants took either the fiber or a placebo powder mixed in water. The researchers measured changes in gut bacteria, fatty acids, and digestive tolerance. This is a small, early study to see if the fiber has any effect.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Chitin-glucan fiber (from Aspergillus niger)
What this could lead to
If it works, this could point toward a simple dietary supplement to improve gut health and reduce cardiometabolic risk.
What could go wrong
This is a very small, early study with only 19 people. Results may not apply to everyone, and the fiber might cause digestive discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Started

Nov 2018

Finished

Jun 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy * Non-smokers * Body mass index between 25 and 35 kg/m2 * Waist circumference \< 80cm for women and \> 94 cm for men * Fiber intake \<25g/day Exclusion Criteria: * Medical history of digestive surgery or disease * Current or recent (\<12 weeks) intake of antibiotics or gastro-intestinal medicinal product * Current probiotics, prebiotics, fiber complement, and/or any products modulation gut transit * Feeding particular diet such as vegetarian diet or hyperprotein diet * Current weight loss diet * Pregnant or lactating woman or woman who did not use effective contraception * Drinking more than 3 glasses of alcohol per day (\>30g/day)

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Conditions

The condition(s) this trial relates to.

Obesity, Abdominal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal obesity Cardiometabolic risk

Contacts and locations

Locations

  • Centre de Recherche en Nutrition Humaine Rhône-Alpes - Centre hospitalier Lyon Sud

    Pierre-Bénite, 69310, France

More trials for these conditions

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