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Probiotic pill may shield elite footballers from travel gut troubles

NCT ID NCT07585474

Disease control Sponsor: Sheffield Hallam University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how long-haul travel and pre-season training affect the gut microbiome and immune function of elite footballers. Thirty male players will take either a daily probiotic capsule or a placebo for several weeks. Researchers will collect stool and saliva samples to see if the probiotic helps keep the gut stable and supports immune health during travel and heat training.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Probiotic capsule
What this could lead to
If it works, this could point toward a simple probiotic supplement to help athletes maintain gut health and immune function during travel and intense training.
What could go wrong
This is a small, early-stage trial in a very specific group (elite male footballers), so results may not apply to others. The probiotic may show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male professional footballers who are involved in regular training during the pre-season period. * Generally healthy, with no acute or chronic illnesses that could interfere with the study intervention or outcomes. * Not currently consuming probiotics, prebiotics, or antibiotics within 4 weeks prior to enrolment. * Willing to refrain from starting any new dietary supplements or probiotics during the study period. * Able and willing to provide written informed consent. Exclusion Criteria: * History of gastrointestinal disorders (e.g., Crohn's disease, ulcerative colitis, irritable bowel syndrome) or chronic diseases that could interfere with probiotic metabolism or study outcomes. * Acute illness (e.g., infection) within 2 weeks prior to enrollment. * Known allergy or hypersensitivity to components of the probiotic or placebo. - - - Use of antibiotics, probiotics, prebiotics, or synbiotics within 4 weeks prior to study start. * Use of immunosuppressive medications or other supplements likely to impact gut microbiota. * Regular use of alcohol or drugs at levels that could interfere with study participation or outcomes. * Participation in another clinical trial within the past 3 months. * Any injury or medical condition that limits participation in full training or matches during the study period.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Immune function Microbial composition

How to take part

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  1. The places running it

    2 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • 1 Hotel Nashville

    Nashville, Tennessee, 37203, United States

  • Bodymoor Heath

    Tamworth, West Midlands, B78 2BB, United Kingdom

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