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Gut bugs and night shifts: a recipe for diabetes risk?
NCT ID NCT05251207
First seen Jun 27, 2026 · Last updated Aug 18, 2026 · Updated 2 times
Summary
This study looks at how a substance made by gut bacteria, called TMAO, might affect insulin resistance (a step toward diabetes). Researchers will give 40 healthy adults L-carnitine supplements and also have them do a simulated night-shift to see how these factors change blood markers related to diabetes and inflammation. The goal is to understand the connection, not to treat or cure any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Feb 2022
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy volunteers, * must be able to swallow tablets Exclusion Criteria: * smokers, * cardiovascular disease * liver disease * kidney disease * gastrointestinal disorders (including stomach ulcers and erosions) * diabetes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Akademia Wychowania Fizycznego
Poznan, 61-871, Poland
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Other studies related to the condition(s) this trial covers.
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