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Gum recession showdown: which membrane works best?

NCT ID NCT07308405

Disease control Sponsor: Institute of Dental Sciences, Bareilly, Uttar Pradesh, India Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two surgical techniques for fixing receding gums in 50 adults aged 18-35. Both methods used a coronally advanced flap, but one added a platelet-rich fibrin membrane and the other a chorion membrane. The goal was to see which better reduces gum recession and improves gum attachment over 6 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
platelet-rich fibrin (PRF) membrane and chorion membrane (CM)
What this could lead to
If one method proves better, it could offer a more effective way to treat receding gums and improve gum health.
What could go wrong
This is a small, completed trial with only 50 participants. The results may not apply to everyone, and both procedures are surgical with typical risks like infection or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Dec 2015

Finished

Oct 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-35 years * In good general health * Isolated Miller's Class I or II gingival recession ≥ 2 mm * ≥ 1 mm keratinised tissue apical to root exposure * Identifiable CEJ (cementoenamel junction) Exclusion Criteria: * Poor oral hygiene after Phase I therapy * Smoking or alcohol use * Occlusal disharmony * Parafunctional habits * Non-vital or endodontically treated teeth * Caries, restorations, or crowns at the CEJ * Frenum pull at the attached gingiva * Previous surgery in the area

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Conditions

The condition(s) this trial relates to.

gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingival recession

Contacts and locations

Locations

  • Department of Periodontics and implantology , Institute of Dental sciences, Bareilly, Uttar Pradesh, India

    Bareilly, Uttar Pradesh, India

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