New pill takes on hard-to-treat tumors in early trial
NCT ID NCT07213609
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times
Summary
This study tests an experimental oral drug (GSK5460025) in adults with advanced solid tumors that have specific genetic features (dMMR or MSI-H), which often make them harder to treat. The trial has two parts: first, finding a safe dose and checking for side effects; second, seeing if the drug alone or with other cancer treatments can shrink tumors. About 47 participants will take part, and the goal is to learn if the drug is safe and effective.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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GSK Investigational Site
RECRUITINGCanton, Ohio, 44718, United States
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GSK Investigational Site
RECRUITINGNashville, Tennessee, 37203, United States
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GSK Investigational Site
RECRUITINGHamilton, Ontario, L8V 5C2, Canada
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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GSK Investigational Site
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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GSK Investigational Site
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
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GSK Investigational Site
RECRUITINGChiba, 277-8577, Japan
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GSK Investigational Site
RECRUITINGOsaka, 573-1191, Japan
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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GSK Investigational Site
RECRUITINGTokyo, 104-0045, Japan
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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GSK Investigational Site
RECRUITINGTokyo, 135-8550, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.