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PET scans could revolutionize monitoring of rare inflammatory disease

NCT ID NCT07712172

Knowledge-focused Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study explores whether a special type of PET/CT scan, using a radioactive tracer called 18F-FDG, can accurately measure disease activity in people with granulomatosis with polyangiitis (GPA), a rare condition that causes inflammation of blood vessels. Researchers will compare the scan results with a standard clinical scoring system to see if the imaging technique can provide a more objective way to track the disease. The study involves 31 adults with newly diagnosed or relapsed active GPA.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
18F-FDG (a radioactive tracer used in PET/CT scans)
What this could lead to
If successful, this could lead to a more accurate, non-invasive way to monitor GPA disease activity, potentially improving treatment decisions.
What could go wrong
This is a small, early observational study, so results may not apply broadly. The scan's sensitivity and correlation with standard scores may be limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

31 people

The number who actually took part.

Started

Jan 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Newly diagnosed/ relapsed active GPA patients with BVAS v3 more than or equal to 1.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients with newly diagnosed or relapsed active GPA, Age more than or equal to18 years. Exclusion Criteria: Pregnant/ lactating women and non-consenting adults

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Conditions

The condition(s) this trial relates to.

granulomatosis with polyangiitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Granulomatosis with polyangiitis (Wegener's)

Contacts and locations

Locations

  • Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh

    Chandigarh, Chandigarh, 160012, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.