Post Graduate Institute Of Medical Education And Research, Chandigarh

This study tests whether adding empagliflozin (a diabetes drug) to standard carvedilol treatment can prevent liver decompensation events and death in 400 adults with cirrhosis and left ventricular diastolic dysfunction (stiff heart). Participants will receive either empagliflozin…

This study looks at people with a mix of two lung conditions caused by the fungus Aspergillus: chronic pulmonary aspergillosis and allergic bronchopulmonary aspergillosis. Researchers want to see if adding steroid pills to the standard antifungal drug itraconazole works better th…

Doctors struggle to find the cause of pyrexia of unknown origin, a fever of at least 38.3°C lasting three weeks or more that routine tests cannot explain. This study compares two imaging approaches as the first scan: FDG-PET/CT, which highlights tissues with unusual glucose use, …

Researchers are testing whether a six-week home-based pulmonary rehabilitation program can improve quality of life and exercise capacity in adults with interstitial lung disease. Participants are randomly assigned to either the home exercise program with weekly phone check-ins or…

This study tests whether dexmedetomidine, a sedative, works better than midazolam for keeping patients comfortable during medical thoracoscopy—a procedure where doctors look inside the chest cavity. About 56 adults with unexplained fluid around the lungs will be randomly assigned…

This study tests whether pregabalin, a drug used for nerve pain, can reduce chronic itching in people with type 2 diabetes. 46 adults will receive either pregabalin plus moisturizer or a placebo plus moisturizer for 12 weeks. Researchers will measure itching severity and quality …

This study looks at why some pregnant women develop intrahepatic cholestasis of pregnancy (ICP), a liver condition causing severe itching and higher risks for both mother and baby. Researchers will measure bile acids and check for genetic changes in 150 Indian women with and with…

This study will check for microplastics in liver tissue from 30 people with cirrhosis who are having surgery or a liver transplant. Researchers want to see if these tiny plastic particles are linked to worse liver damage, higher blood pressure in the liver, and heart problems. Th…

This study looks at whether feeding through a tube into the small intestine is better than eating by mouth after a procedure to drain a pancreatic cyst caused by severe pancreatitis. About 50 adults with this condition will be randomly assigned to one of the two feeding methods. …

This study compares two ways to manage fluids in cirrhosis patients with severe sepsis or septic shock. One method uses a bedside heart ultrasound (POCUS) to guide fluid amounts, while the other follows standard sepsis guidelines. The goal is to see if ultrasound-guided care redu…