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Pausing GLP-1 drugs before surgery: new study aims to find the sweet spot

NCT ID NCT07623148

Knowledge-focused Sponsor: Wonkwang University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 7 times

Summary

This study watches 186 adults who take GLP-1 drugs (like Ozempic) and are having planned surgery. Researchers use a stomach ultrasound to check how much food or liquid is left in the stomach after stopping the drug for different lengths of time. The goal is to see if longer pauses lead to emptier stomachs, which may lower the risk of complications during anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors give clearer guidance on when to pause GLP-1 drugs before surgery to reduce the risk of food or liquid remaining in the stomach.
What could go wrong
This is an observational study, not a treatment trial. It only measures stomach contents with ultrasound and does not test any new drug or intervention. Results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

186 people

The number who actually took part.

Started

Jul 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients receiving glucagon-like peptide-1 receptor agonists who are scheduled for elective non-cardiac surgery requiring general anesthesia at a tertiary academic hospital. Participants will be screened consecutively by the perioperative anesthesia team and enrolled if eligibility criteria are met.

Ages

19 to 65 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Patients receiving a glucagon-like peptide-1 receptor agonist. * Patients scheduled for elective non-cardiac surgery requiring general anesthesia. * Patients able to provide written informed consent. Exclusion Criteria: * Emergency surgery. * History of prior gastric surgery. * Known gastroparesis or severe gastroesophageal reflux disease. * Declined or unable to provide written informed consent.

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Conditions

The condition(s) this trial relates to.

gastroparesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delayed gastric emptying Residual gastric contents

Contacts and locations

Locations

  • Wonkwang University School of Medicine Hospital

    Iksan, Jeonbuk-do, 54538, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.