New MRI technique could help surgeons predict brain tumor toughness
NCT ID NCT05990244
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study uses a special MRI technique called magnetic resonance elastography (MRE) to measure how stiff and sticky brain tumors (gliomas) are. Researchers will compare these measurements with what surgeons see during operations and with the tumor's genetic makeup. The goal is to see if MRE can help predict tumor behavior and guide treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Magnetic Resonance Elastography (MRE)
- What this could lead to
- If successful, this could help doctors better predict tumor behavior and tailor surgeries for glioma patients.
- What could go wrong
- This is an early observational study with only 100 participants, so results may not apply to all patients. MRE is not yet standard for glioma assessment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2017
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. age older than 18 years 2. Karnofsky performance status higher than 60 3. with written informed consent 4. MRE performed within one week before surgery 5. tumor diameter \> 2 cm Exclusion Criteria: 1. previous treatment for glioma 2. inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia) 3. completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude) 4. failure to proceed with surgery after MRE 5. missing IDH results
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shengjing Hospital
RECRUITINGShenyang, Liaoning, 110000, China
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