Gene study aims to predict stroke outcomes
NCT ID NCT07269288
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how changes in the GGCX gene relate to recovery after an ischemic stroke. Researchers will collect blood samples from 1,500 stroke patients and follow them for 12 months to track strokes, bleeding, and deaths. The goal is to understand if this gene can help predict who will have better or worse outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict stroke outcomes and personalize treatment based on a patient's genes.
- What could go wrong
- This is an observational study, not a treatment trial. It may find no clear link between the GGCX gene and stroke prognosis, or results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will be conducted in six hospitals (centers) across the country, namely Xi'an Jiaotong University First Affiliated Hospital, Shandong Weifang Second People's Hospital, Shandong Linshu People's Hospital, Hunan Second People's Hospital (Hunan Brain Hospital), and Nantong First People's Hospital.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* Inclusion Criteria (1) Inclusion Criteria for Acute Ischemic Stroke Patients: 1. Aged between 18 and 85 years. 2. Diagnosed with ischemic stroke (in accordance with the "Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2023," including TOAST etiological/pathogenic subtypes: large-artery atherosclerosis (LAA), cardioembolism (CE), small-artery occlusion (SAO), stroke of other determined etiology (SOE), and stroke of undetermined etiology (SUE)). 3. Acute onset, with symptoms occurring within 72 hours and being the first episode. 4. Voluntary participation with signed informed consent. (2) Inclusion Criteria for Healthy Controls: 1) Healthy control population matched for age, gender, and risk factors (including personal and family history). * Exclusion Criteria (1) Exclusion Criteria for Healthy Controls: 1. Patients with cerebrovascular diseases occurring within 72 hours. 2. Pregnant or lactating patients. (2) Exclusion Criteria for Acute Ischemic Stroke Patients: 1. Other types of stroke, including hemorrhagic stroke, mixed stroke, and tumor-related stroke patients. 2. Patients with coagulation disorders or other hematologic diseases. 3. Patients with severe cardiovascular, pulmonary, or hepatic diseases. 4. Renal dysfunction. 5. Cancer patients. 6. Patients with active gastric ulcers or gastric bleeding. 7. Pregnant or lactating patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Peking University Aerospace Center Hospital
Beijing, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- China builds national watchdog for brain blood vessel devices
- Can tiny neural exosomes help the brain heal after a severe stroke?
- Can a new antibody boost recovery after severe stroke?
- After stroke, a balloon or a stent? trial tests which rescue opens blocked brain arteries better