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New drug targets Hard-to-Treat cancers with RAS mutations

NCT ID NCT07198321

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 27 times

Summary

This study tests a new drug called GFH276 in people with advanced cancers that have RAS mutations, including pancreatic, lung, and colorectal cancers. The goal is to see if the drug is safe and can shrink tumors or slow disease. About 450 adults aged 18-75 will take part in two phases: first to find the right dose, then to measure how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun-Yat sen university cancer center

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.