New drug targets Hard-to-Treat cancers with RAS mutations

NCT ID NCT07198321

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study tests a new drug called GFH276 in people with advanced cancers that have a specific gene change (RAS mutation). The cancers include pancreatic, lung, and colorectal cancer. The goal is to find a safe dose and see if the drug can shrink tumors. About 450 adults aged 18-75 will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun-Yat sen university cancer center

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.