Can a blood test predict who will get diabetes from steroids?
NCT ID NCT04840693
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find genetic and metabolic markers that explain why some people develop diabetes, high blood pressure, or bone loss from glucocorticoids while others do not. Researchers will analyze blood and urine samples from up to 600 participants, including those with excess glucocorticoids, adrenal insufficiency, and control groups. The goal is to create a tool that predicts individual risks, helping doctors personalize treatment and monitoring.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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31 people
The number who actually took part.
- Started
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Aug 2023
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * an endogenous hypercortisolism (group 1) * a disease justifying the next start of glucocorticoid therapy (group 2) * chronic adrenal insufficiency (group 3) * subjects with either diabetes, hypertension or osteoporosis, but without glucocorticoid excess (control group) * patients will have to be affiliated to a social security scheme * patients should be able to understand the study and able to express their consent Exclusion Criteria: * patients with reduced life expectancy, less than 2 years * pregnant or lactating women * patients refusing the protocol * patients under state medical assistance
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Cochin
Paris, 75014, France