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Gene test may personalize heart drug dosing

NCT ID NCT07439952

First seen Mar 19, 2026 · Last updated Jun 09, 2026 · Updated 12 times

Summary

This study looks at how a person's genes affect their response to the heart drug mavacamten for obstructive hypertrophic cardiomyopathy. Researchers will collect DNA samples from 300 patients to see which genetic types respond best. The goal is to improve dosing safety and effectiveness based on genetic differences.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP, Ambroise Paré

    Boulogne-Billancourt, 92100, France

    Contact

    Contact Email: •••••@•••••

  • APHP, Bicêtre hospital

    Le Kremlin-Bicêtre, France

    Contact Email: •••••@•••••

    Contact

  • APHP, La Pitié Salpetriere hospital

    Paris, 75013, France

    Contact Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.