Scientists hunt for sinusitis genes in 1,200-Person study
NCT ID NCT00880516
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the genes of 1,200 adults to find out why some people get chronic sinusitis. Participants must have a CT scan showing either normal sinuses or sinus disease. The goal is to identify genetic variations linked to the condition, which could lead to better understanding and future treatments.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2009
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults with and without chronic sinusitis
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age\> 18 years * Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease. Exclusion Criteria: * Genetic or acquired immunodeficiency * Ciliary dyskinesia * Cystic fibrosis * Autoimmune disease * Cancer of the sinuses
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Chicago
Chicago, Illinois, 60637, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sinus surgery without opioids: can dexmedetomidine do the job?
- Can a drug that calms inflammation ease chronic sinusitis?
- Withdrawn study sought to understand sinus problems in young cancer survivors
- Blood cell study may personalize asthma and sinusitis treatment
- Gentle Hands-On therapy shows promise for sinus sufferers
- New sinus implant aims to unblock noses and ease facial pain