Gentle Hands-On therapy shows promise for sinus sufferers
NCT ID NCT07542444
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding a gentle hands-on therapy called craniosacral osteopathic treatment to standard care can improve symptoms and quality of life for people with chronic sinusitis. Fifty adults with the condition were randomly assigned to receive either standard medical care alone or standard care plus 8 sessions of the therapy over 4 weeks. Researchers measured symptom severity, nasal blockage, pain, and quality of life before, after, and at follow-up.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-65 years * Diagnosis of chronic rhinosinusitis (CRS) confirmed by an otorhinolaryngologist * Presence of at least two of the following symptoms for ≥12 weeks: * Nasal obstruction * Mucopurulent nasal discharge * Facial pain/pressure * Reduced or loss of smell * Ability to provide informed consent Exclusion Criteria: * Acute rhinosinusitis or acute exacerbation of CRS * History of cranial, facial, or cervical surgery within the past year * Neurological or structural conditions contraindicating craniosacral therapy (e.g., intracranial hemorrhage, aneurysm, Chiari malformation) * Cerebrospinal fluid (CSF) leak * Recent manual therapy intervention (within the last 2 months) * Use of additional therapeutic interventions during the study period * Severe cognitive impairment limiting participation or informed consent * Pregnancy (high-risk pregnancy)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alanya Alaaddin Keykubat University
Alanya, Antalya, 07400, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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