Can your genes predict kidney stones? mayo clinic launches huge study
NCT ID NCT01127854
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study from Mayo Clinic looks at whether certain gene variants make people more likely to form calcium oxalate kidney stones. Researchers will compare 2,900 adults with and without a history of kidney stones, analyzing blood samples and lifestyle factors. The goal is to better understand genetic and environmental risks for stone formation and recurrence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify people at higher genetic risk for kidney stones, leading to better prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly change patient care, and genetic findings may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,900 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Dec 2009
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Mayo Clinic in Jacksonville, FL
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Cases: * History of calcium oxalate stones * 18 years of age or older * Willing to provide a blood sample, and questionnaire Controls: * 18 years of age or older * No personal history of urolithiasis * Willing to provide a blood sample and questionnaire Exclusion Criteria: Cases: * Secondary causes of urolithiasis including: Bowel disease, Renal tubular acidosis, hyperparathyroidism
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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