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Gene therapy offers new hope for sickle cell patients

NCT ID NCT03964792

First seen Feb 05, 2026 · Last updated Jun 16, 2026 · Updated 23 times

Summary

This early-phase study tested a gene therapy for sickle cell disease in 6 patients aged 12-20. Doctors took the patients' own blood stem cells, added a working gene to help produce healthy red blood cells, and infused them back after chemotherapy. The goal was to see if the treatment is safe and can reduce severe pain crises and other complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Department of Biotherapy, Necker-Enfants Malades Hospital

    Paris, 75015, France

Conditions

The condition(s) this trial relates to.

sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.