Gene therapy offers new hope for sickle cell patients

NCT ID NCT03964792

First seen Feb 05, 2026 · Last updated Jun 16, 2026 · Updated 23 times

Summary

This early-phase study tested a gene therapy for sickle cell disease in 6 patients aged 12-20. Doctors took the patients' own blood stem cells, added a working gene to help produce healthy red blood cells, and infused them back after chemotherapy. The goal was to see if the treatment is safe and can reduce severe pain crises and other complications.

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Contacts and locations

Locations

  • Department of Biotherapy, Necker-Enfants Malades Hospital

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.