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Massive gene hunt aims to solve mystery of intellectual disability

NCT ID NCT01867554

First seen Jun 10, 2026 · Last updated Jun 23, 2026 · Updated 1 time

Summary

This study looked at 8500 people with intellectual disability to find new genes that might cause it. Researchers used advanced DNA tools to compare patients and their healthy siblings. The goal was to identify unknown genetic causes and improve future diagnosis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CRICM - UPMC/Inserm UMR_S975/CNRS UMR7225, Groupe Hospitalier de la Pitié-Salpêtrière,

    Paris, 750013, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could identify new genes causing intellectual disability, leading to better genetic testing and diagnosis for affected families.

What could go wrong

This is an observational study, not a treatment trial. It may not find new genes or directly benefit participants, and results may take years to apply.

Conditions

The condition(s) this trial relates to.

Autism Spectrum Disorder intellectual disability

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.