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Garlic vs. standard root canal medicine: a tooth showdown!

NCT ID NCT07289971

Disease control Sponsor: University of Health Sciences Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if garlic gel can replace the usual medicine placed inside teeth during root canals. About 96 people with infected permanent teeth will get either garlic gel or calcium hydroxide. Researchers will check pain, swelling, and X-ray healing to see if garlic works as well. If successful, garlic could offer a cheaper, natural option for dental care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 96 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with the physical status of ASA I and ASA II according to ASA classification. * Patients aged from 15-45 years. * Mature permanent single-rooted teeth with closed apices. * Patients with clinical signs of symptomatic apical periodontitis (pain, tenderness to palpation, and percussion). * Patients having radiographic evidence of periapical radiolucency of endodontic origin. * Patients who have not taken antibiotics for the past 14 days. * Cooperative patients who show good compliance. Exclusion Criteria: * Patients with physical status of ASA III, IV, and V according to ASA classification. * Teeth with a calcified pulp chamber in periapical radiography. * Patients who have undergone previous endodontic treatment failure and those with the presence of sinus tract on clinical examination. * Teeth having advanced periodontal disease, with the basic periodontal examination (BPE) of 3 and 4. * Presence of internal and external resorption of the root as viewed on the periapical radiograph. * Presence of vertical root fracture and perforation as viewed on the periapical radiograph

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Conditions

The condition(s) this trial relates to.

periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Apical periodontitis Periapical radiolucency

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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More trials for these conditions

Other studies related to the condition(s) this trial covers.