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Knife or no knife? new trial tests surgery for wrist lumps

NCT ID NCT07162415

Symptom relief Sponsor: Tampere University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to treat painful wrist ganglions (fluid-filled lumps). Half of the 220 adult participants will have surgery to remove the ganglion, while the other half will do exercises and use their hand normally. Researchers will measure pain, function, and satisfaction over 6 to 12 months to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgery (open or arthroscopic resection)
What this could lead to
If surgery proves better than exercises, it could become the preferred treatment for painful wrist ganglions.
What could go wrong
This is a relatively small trial (220 people) and results may not apply to everyone. Surgery also carries risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 220 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2035

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * wrist pain located in the ganglion area * diagnosis of ganglion of the wrist, based on clinical examination or imaging findings * age over 18 years * ability to fill out the Finnish or English version of the questionnaires Exclusion Criteria: * pregnant or breast feeding * other known wrist pathology that likely explains the pain * previous surgical treatments of the wrist * wrist ganglion presumed to be related to a work injury

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Conditions

The condition(s) this trial relates to.

connective tissue disorder cutaneous mucinosis Ganglion Cysts ganglion or cyst of synovium/tendon/bursa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Connective tissue disease Ganglion Ganglion cyst Mucinoses Wrist ganglion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Helsinki University Hospital

    NOT_YET_RECRUITING

    Helsinki, 00029, Finland

  • Hospital Nova of Central Finland

    NOT_YET_RECRUITING

    Jyväskylä, 40620, Finland

  • National University Hospital

    NOT_YET_RECRUITING

    Singapore, 119228, Singapore

  • Tampere University Hospital

    RECRUITING

    Tampere, 33521, Finland

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