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Which pill works better for Post-Surgery pain? study pits gabapentin against diclofenac

NCT ID NCT07267182

Symptom relief Sponsor: Muhammad Aamir Latif Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared a single dose of gabapentin (600 mg) versus diclofenac sodium (100 mg) given one hour before major abdominal surgery to see which provides better pain relief afterward. A total of 240 adults aged 18 to 60 took part. Pain was measured using a standard pain scale, and effective relief was defined as a score of 3 or less without needing extra pain medicine.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
gabapentin and diclofenac sodium
What this could lead to
If effective, this could help doctors choose a better single-dose painkiller for patients before major abdominal surgery.
What could go wrong
This is a small, completed trial with no phase designation, so results may not apply to all surgeries or patients. Pain relief was measured only in the short term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

240 people

The number who actually took part.

Started

Aug 2022

Finished

Feb 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Any gender * Aged 18-60 years * Undergoing elective major abdominal surgery under general anesthesia * With physical status I or II * Who were able to comprehend and use the Visual Analogue Scale (VAS) for pain assessment Exclusion Criteria: * With a known allergy or contraindication to gabapentin, or diclofenac sodium * A history of peptic ulcer disease * A history of gastrointestinal bleeding * Hepatic or renal dysfunction * Pregnancy or lactation * With neurological or psychiatric disorders affecting pain perception * Received opioids, anticonvulsants, antidepressants, or nonsteroidal anti-inflammatory drugs (NSAIDs) within 24 hours before surgery * With uncontrolled hypertension, ischemic heart disease, or diabetes mellitus * Those who experienced intraoperative complications necessitating a change in anesthetic plan or postoperative mechanical ventilation

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain

Contacts and locations

Locations

  • Bahawal Victoria Hospital

    Bahawalpur, Punjab Province, 63100, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.