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Study reveals hidden toll of common infections on Seniors' independence

NCT ID NCT07388173

Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how serious respiratory infections (like flu, COVID-19, and RSV) affect the ability of adults aged 60 and older to live independently. Researchers will follow 1,600 hospitalized seniors across multiple countries to track changes in daily activities such as bathing, dressing, and managing medications. The goal is to better understand which infections cause the most functional decline and to help design better prevention and vaccination programs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will include participants aged 60 years or older who are hospitalized with a serious acute respiratory infection in the departments of infectious diseases, geriatrics, internal medicine, pulmonology, or emergency medicine. Recruitment will be conducted by investigator physicians in each participating department. Potentially eligible participants will be identified by daily screening of admission records and results from standard of care respiratory samples. Each country will aim to recruit approximately 320 participants - 80 with each pathogen of interest. Efforts will be made to secure an equal distribution of participants aged 60-75 and \>75 years age.

Ages

60 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female subjects aged 60 years or older * Hospitalized in a study center (emergency department, infectious disease, internal medicine or geriatric hospital wards…) for acute respiratory infection (refer to table 1 below for definition). * Confirmed positive PCR test for influenza, SARS-CoV-2, RSV, or human metapneumovirus (hMPV). Participants with co-infections with other viral or bacterial agents can be included. Exclusion Criteria: * Participants with conditions significantly impacting short-term functional status, such as severe disability (ADL score ≤2 or Clinical Frailty Scale ≥7), terminal illness, palliative care needs, or inability to comprehend and complete study questionnaires due to severe stroke sequelae, complete sensory loss, advanced dementia, or similar impairments. * Participants that refuse or are unable to answer the 3- and 6-months follow-up phone call assessments * Positive laboratory test for single (mono-infection) virus other than influenza, SARS-CoV-2, RSV, or human metapneumovirus (HMPV) * Participant in exclusion period for another study using an investigational / unapproved medicinal product. * Participant referred to in articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons : pregnant woman, parturient, breastfeeding mother, person deprived of liberty by judicial or administrative decision, persons undergoing psychiatric care under articles L.3212-1 and L.3213-1 who do not fall under article L.1121-8, persons admitted to a healthcare or social institution for purposes other than research, minors, person under legal protection or unable to express consent). * Individuals opposed to participating in the research * Staff members with a hierarchical relationship to the principal investigator

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Conditions

The condition(s) this trial relates to.

COVID-19 influenza respiratory syncytial virus infectious disease respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Respiratory infections in old age

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    19 sites in 5 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • APSS Trento, Geriatria, Trento

    NOT_YET_RECRUITING

    Trento, Italy

  • ASL 1 Imperiese, Sanremo

    NOT_YET_RECRUITING

    Sanremo, Italy

  • ASUGI, Trieste

    NOT_YET_RECRUITING

    Trieste, Italy

  • Abteilung Geriatrie Universitätsmedizin Göttingen, Abteilung Geriatrie

    NOT_YET_RECRUITING

    Göttingen, Germany

  • Azienda Ospedaliero Universitaria "Renato Dulbecco", Catanzaro

    NOT_YET_RECRUITING

    Catanzaro, Italy

  • Città di Torino, Torino

    NOT_YET_RECRUITING

    Torino, Italy

  • Hospital Clínic Barcelona Servicio de Geriatría

    RECRUITING

    Barcelona, Spain

  • Hospital Universitario Ramón y Cajal. Madrid Servicio de Geriatría

    NOT_YET_RECRUITING

    Madrid, Spain

  • Hospital Universitario Virgen de la Arrixaca Murcia Servicio de Geriatría

    NOT_YET_RECRUITING

    Murcia, Spain

  • Klinikum Bayreuth, Klinik für Geriatrie

    NOT_YET_RECRUITING

    Bayreuth, Germany

  • Klinikum Ulm, Geriatrisches Zentrum Agaplesion Bethesda

    NOT_YET_RECRUITING

    Ulm, Germany

  • Melun Hospital

    RECRUITING

    Melun, France

  • ULSS 3 Serenissima, Venice

    NOT_YET_RECRUITING

    Venice, Italy

  • ULSS 5 Polesana, Rovigo

    NOT_YET_RECRUITING

    Rovigo, Italy

  • ULSS 9 Scaligera, Legnago, Verona

    NOT_YET_RECRUITING

    Verona, Italy

  • Uniklinikum Jena, Klinik für Geriatrie

    NOT_YET_RECRUITING

    Jena, Germany

  • University Hospital of Amiens

    ACTIVE_NOT_RECRUITING

    Amiens, France

  • University Hospital of Poitiers

    ACTIVE_NOT_RECRUITING

    Poitiers, France

  • University Hospital of Reims

    ACTIVE_NOT_RECRUITING

    Reims, France

  • University Hospital of Tours

    ACTIVE_NOT_RECRUITING

    Tours, France

  • University of Bari, Bari

    NOT_YET_RECRUITING

    Bari, Italy

  • University of Rochester School of Medicine, Infectious Diseases Unit

    RECRUITING

    Rochester, New York, 14642, United States

  • Universitätsmedizin Mannheim, IV. Medizinische Klinik (Geriatrie)

    NOT_YET_RECRUITING

    Mannheim, Germany

  • Villeneuve Saint Georges Hospital

    ACTIVE_NOT_RECRUITING

    Paris, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.